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Smiles: CC1C=C(NC2=CC(NC3=CC=CC=C3C(=O)NOC)=C(Cl)C=N2)N(N=1)C(C)C
A method for quantifying therapeutic antibodies
with IC50s of 8
157(3):433-40
GATA4-NKX2-5-IN-1 Catalog No.:M13158-10 Smiles: CC1C=C(NC2=CC(NC3=CC=CC=C3C(=O)NOC)=C(Cl)C=N2)N(N=1)C(C)CGATA4 NKX2 5 IN 1 (Compound 3) dose dependently inhibits the GATA4NKX2 5 transcriptional synergy with an IC50 of 3 M. GATA4 NKX2 5 IN 1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist induced cardiac gene expression. Product information CAS Number: 544681 96 1 Molecular Weight: 349. 43 Formula: C21H23N3O2 Chemical Name: N [4 (diethylamino)phenyl] 5 methyl 3
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