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JAK-IN-1 Size:Contact [email protected] for quotation ) administration transforms a short-term

SKU: 13004199182

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Description

) administration transforms a short-term learning event into a long-term remembered experience in WT but not in histamine-depleted mice

InChiKey: WECGLUPZRHILCT-HZJYTTRNSA-N

is a potent and selective type 1 inhibitor of FLT3 that retains its cellular potency against clinically relevant secondary resistance mutations in FLT3 occurring with quizartinib or sorafenib treatment (FLX925 IC50: MOLM13ITD

MicroPET imaging up to 24 post-injection showed contrasting tumors reflecting αvβ3-targeted tracer accumulation

JAK-IN-1 Size:Contact [email protected] for quotation ) administration transforms a short-termJAK IN 1 is a JAK1 2 3 inhibitor with IC50s of 0. 26, 0. 8 and 3. 2 nM, respectively. JAK IN 1 shows improved selectivity for JAK3 over JAK1. Product information CAS Number: 1334673 53 8 Molecular Weight: 380. 44 Formula: C20H24N6O2 Chemical Name: N [(2R) 1 (3 cyanoazetidin 1 yl) 3,3 dimethyl 1 oxobutan 2 yl] 2 cyclopropyl 5H pyrrolo[2,3 b]pyrazine 7 carboxamide Smiles: CC(C)(C)[C@@H](NC(=O)C1=CNC2=NC=C(N=C12)C1CC1)C(=O)N1CC(C1)C#N InChiKey:

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