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Endocrinology
Formula: C25H23N5O2S
Momelotinib Mesylate (CYT387 Mesylate) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM
Terbinafine is a synthetic antifungal agent inhibiting fungal squalene epoxidase
BEZ235 - CAS# 915019-65-7 urinol EndocrinologyDactolisib, also known as BEZ235, is an orally bioavailable phosphatidylinositol 3 kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BEZ235 specifically inhibits PIK3 in the PI3K AKT kinase (or protein kinase B) signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability; apoptotic cell death may ensue. Bax is a member of the
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