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PubMed PMID: 6538512
335(1):62-7
After treatment with U0126
MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat
PF-06826647 Size:100mg solid PubMed PMID: 6538512PF 06826647 (Tyk2 IN 8, compound 10) is a selective and orally administered inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 17 nM for binding to TYK2 catalytically active JH1 domain. PF 06826647 (Tyk2 IN 8, compound 10) also inhibits JAK1 and JAK2 with IC50 of 383 nM and 74 nM, respectively. PF 06826647 (Tyk2 IN 8, compound 10) is used in the treatment of psoriasis (PSO). Product information CAS Number: 2127109 84 4 Molecular Weight: 383. 41