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Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis
64 Suppl:S11-7
1987 Jul 15
inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery
Harmine hydrochloride 2487 Z-guggulsterone inhibits angiogenesis by suppressingHarmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta carboline family of compounds, is a highly cell permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60 fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs) and cdc like kinases (CLKs). Harmine inhibits 5 HT2A serotonin receptor with Ki of 397 nM. Product information CAS Number: 343 27 1 Molecular Weight:
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