CAS No. 10009-70-8 Catalog No.:M35131-C 0 nM of Pz-1 strongly

0 nM of Pz-1 strongly inhibits tyrosine phosphorylation of VEGFR2 and clinically relevant RET mutants

5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-3-methoxyoxolan-2-yl]-2-oxo-1

3-dihydro-1H-isoindol-5-yl}-1-methyl-1H-pyrazole-4-carbonitrile

but Niraparib S-enantiomer is more potent in cell based assays (PARylation EC50

CAS No. 10009-70-8 Catalog No.:M35131-C 0 nM of Pz-1 stronglyProduct information CAS Number: 10009 70 8 Molecular Weight: 152. 97 Formula: C3H5BrO2 Chemical Name: (2R) 2 bromopropanoic acid Smiles: C[C@@H](Br)C(O)=O InChiKey: MONMFXREYOKQTI UWTATZPHSA N InChi: InChI=1S C3H5BrO2 c1 2(4)3(5)6 h2H,1H3,(H,5,6) t2 m1 s1 Technical Data Appearance: Solid Power Purity: 95% (or refer to the Certificate of Analysis) Solubility: To be determined Shipping Condition: Shipped under ambient temperature as non hazardous