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10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B
EPZ 004777
PubMed PMID: 24829950
InChi: InChI=1S/C20H23N3O2/c1-16-14-20(25-13-10-22-8-11-24-12-9-22)21-23(16)19-7-6-17-4-2-3-5-18(17)15-19/h2-7
Glibenclamide Catalog No.:M10286-10 10-100 fold more potent inBendectin (old formulation) contains dicyclomine, doxylamine succinate, pyridoxine; in the U. S., dicyclomine has been removed from the combination because it was ineffective. Pyridoxine doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B6) and doxylamine succinate. It is generally used for nausea and vomiting of pregnancy (morning sickness). Product information CAS Number: 10238 21 8
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