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GSK0660 (100 nM) reduces CPT1a (a PPARβ/δ target gene) expression below the basal vehicle-treated level by approximately 50%
3851/IMP2988
selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs
PubMed PMID: 21465936
SR-59230A oxalate - CAS# 174689-39-5 Catalog No.:M7124-2 GSK0660 (100 nM) reduces CPT1aSR 59230A oxalate, CAS No. 174689 39 5, is a potent and selective 3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for 3, 1 and 2 receptors respectively). SR 59230A was subsequently shown to also act at 1 adrenoceptors at high doses. It has been shown to block the hyperthermia produced by MDMA in animal studies. SR 59230A blocks MDMA induced hyperthermia, while at high concentrations it blocks hyperthermia but also increases heat loss
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