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Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel
Smiles: CC1=CC(Br)=C(O)C2=NC=CC=C21
making this inhibitor a valuable tool for investigating the role of EZH2 and EZH1 in chronic animal studies
Smiles: OC1=CC=CC=C1C(=O)NC1=CC=C(Cl)C=C1CN1C(=O)C2=CC=CC=C2C1=O
Gatifloxacin Catalog No.:M10548-10 Apilimod inhibits IL-12 and IL-23Gatifloxacin is an antibiotic of the fourth generation fluoroquinolone family that inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Gatifloxacin is a fluoroquinolone antibiotic, with potent activity against Gram negative and Gram positive bacteria. Bristol Myers Squibb introduced Gatifloxacin in 1999 under the proprietary name Tequin for the treatment of respiratory tract infections. Allergan produces it in eye drop formulation under
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