Apramycin Size:Solid 10 mg Activation of mTORC1 (indicated by

Activation of mTORC1 (indicated by p-S6K1 and p-4E-BP1) and mTORC2 is almost blocked by WAY-600 (100 nM)

with an IC50 of 2 nM

is efficacious in modulating gene transcriptions that are involved in proinflammatory changes of mesangial cells

PubMed Central PMCID: PMC2849388

Apramycin Size:Solid 10 mg Activation of mTORC1 (indicated byApramycin is an antibiotic and the most complex of the nebramycin factors. Product information CAS Number: 37321 09 8 Molecular Weight: 539. 58 Formula: C21H41N5O11 Synonym: Nebramycin II Chemical Name: (2R,3R,4S,5S,6S) 2 {[(2R,3S,4R,4aR,6S,7R,8aS) 7 amino 6 {[(1R,2R,3S,4R,6S) 4,6 diamino 2,3 dihydroxycyclohexyl]oxy} 4 hydroxy 3 (methylamino) octahydropyrano[3,2 b]pyran 2 yl]oxy} 5 amino 6 (hydroxymethyl)oxane 3,4 diol Smiles: