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64(4):932-45
1-6H3/t12-
InChi: InChI=1S/C28H40N6O/c1-3-4-13-29-28-30-18-25-26(20-34(27(25)31-28)23-9-11-24(35)12-10-23)22-7-5-21(6-8-22)19-33-16-14-32(2)15-17-33/h5-8
shows inhibitory activity
CDK4/6-IN-2 indalone 64(4):932-45CDK4 6 IN 2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2. 7 and 16 nM for CDK4 and CDK6, respectively. Product information CAS Number: 1800506 48 2 Molecular Weight: 506. 59 Formula: C27H32F2N8 Chemical Name: 5 [(4 ethylpiperazin 1 yl)methyl] N {5 fluoro 4 [4 fluoro 2 methyl 1 (propan 2 yl) 1H 1,3 benzodiazol 6 yl]pyridin 2 yl}pyrimidin 2 amine Smiles:
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