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Hemmings HC Jr
3-triazol-1-yl]-1-(2
and BT474 and HCC-1954 breast carcinoma xenografts
tight-binding inhibitor of the LpxC deacetylase from the hyperthermophile Aquifex aeolicus
ENMD-1198 Size:2mg solid Hemmings HC JrENMD 1198 (IRC 110160), an orally active microtubule destabilizing agent, is a 2 methoxyestradiol analogue with antiproliferative and antiangiogenic activity. ENMD 1198 is suitable for inhibiting HIF 1alpha and STAT3 in human HCC cells and leads to reduced tumor growth and vascularization. Product information CAS Number: 864668 87 1 Molecular Weight: 311. 42 Formula: C20H25NO2 Synonym: IRC 110160 Chemical Name: (3aS, 3bS, 9bS, 11aR) 8 methoxy 11a
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