Emavusertib - CAS# 1801344-14-8 ericin B is a potent and selective

is a potent and selective allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor with IC50 ~ 230 nM

chemokine receptor CXCR4

2ClH/c14-5-7-17(20

Formula: C23H32ClNO7

Emavusertib - CAS# 1801344-14-8 ericin B is a potent and selectiveEmavusertib, also known as CA 4948 is a potent IRAK4 FLT3 inhibitor with anti tumor activity. CA 4948 demonstrated good cellular activity in ABC DLBCL and AML cell lines. CA 4948 demonstrated moderate to high selectivity in a panel of 329 kinases as well as exhibited desirable ADME and PK profiles including good oral bioavailability in mice, rat, and dog and showed >90% tumor growth inhibition in relevant tumor models with excellent correlation with