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SJF 8240 Catalog No.:M7582-2 Tosedostat (CHR-2797) is an orally

SKU: 98076525855

4.1
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Description

Tosedostat (CHR-2797) is an orally active aminopeptidase inhibitor

a protein that plays an important role in fungal cell wall integrity

5(5):491-503

Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors

SJF 8240 Catalog No.:M7582-2 Tosedostat (CHR-2797) is an orallyc MET PROTACDegrader. Comprises MET inhibitor foretinib (GSK 1363089; Cat. No. 6056) joined by a linker to a von Hippel Lindau (VHL) recruiting ligand. Degrades c MET within 6 hours in vitro. Inhibits agonist driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66. 7 nM). Also degrades exon 14 deleted c MET in Hs746T cells. Product information CAS Number: 2230821 68 6 Molecular Weight: 1106. 24 Formula: C58H65F2N7O11S Synonym: SJF 8240

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