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AZ82 0555 It reduces antigen-induced histamine release

SKU: 9449585686

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Description

It reduces antigen-induced histamine release from rat conjunctival tissue by 46% in vitro when used at a concentration of 10 µg/ml

Chemical Name: 1-(2-Ethylphenoxy)-3-[[(1S)-1

5-difluorophenyl)-3-hydroxy-4-(1H-1

every other day for 4 weeks) significantly reduces the tumor volume in HepG2 subcutaneous xenograft model

AZ82 0555 It reduces antigen-induced histamine releaseAZ82 is a selective kinesin like protein KIFC1 (HSET KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1. Product information CAS Number: 1449578 65 7 Molecular Weight: 560. 63 Formula: C28H31F3N4O3S Chemical Name: (2R) 2 [(5 methyl 4 propylthiophen 2 yl)formamido] N [(3R) pyrrolidin 3 yl] 3 {6 [3 (trifluoromethoxy)phenyl]pyridin 3 yl}propanamide Smiles: CC1SC(=CC=1CCC)C(=O)N[C@H](CC1C=NC(=CC=1)C1=CC(=CC=C1)OC(F)(F)F)C(=O)N[C@H]1CNCC1

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