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PIM1-IN-1 Size:Contact [email protected] for quotation It is showed that ME

SKU: 85575375992

4.0
USD100.00 USD122.00

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Description

It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L

C1[C@@H]2C[C@@H]3CC1(C[C@H](C2)C3)N/C(=N\C1CCCCC1)/N1CCOCC1

Smiles: CN(C(=O)[C@@H]1[C@H](O)CCN1C1=NC(C)=CC(=C1C#N)C(F)(F)F)C1C=CC=C(C)C=1

which might contribute to the anthelmintic effect

PIM1-IN-1 Size:Contact [email protected] for quotation It is showed that MEPIM1 IN 1 is a potent and highly selective PIM1 3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1 IN 1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti cancer activity. Product information CAS Number: 1417630 95 5 Molecular Weight: 474. 56 Formula: C25H30N8O2 Chemical Name: 2 [10 (2 methoxyethyl)

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