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Plinabulin Catalog No.:M10736-2 InChi: InChI=1S/C17H17BrN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7

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Description

InChi: InChI=1S/C17H17BrN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7

TCID can diminish glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons

T16A(inh)A01

Smiles: CC[C@H](NC(=O)[C@H](CS(=O)(=O)CC1CC1)N[C@@H](C1=CC=C(F)C=C1)C(F)(F)F)C(=O)C(=O)NC1CC1

Plinabulin Catalog No.:M10736-2 InChi: InChI=1S/C17H17BrN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7MBRI 001 is a deuterium substituted plinabulin derivative as a potent anti cancer agent. MBRI 001 exhibited better pharmacokinetic characteristics than that of plinabulin. Additionally, its antitumor activity is in a low nanomolar level for a variety of cancer cell lines and high activity against human NCI H460 xenograted in mice intravenous administration. Importantly, continuous administration of MBRI 001 exhibited lower toxicity compared to

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