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shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ
DJ001 treatment also significantly increases the numbers of colony forming cells (CFCs) in 3 day culture of BM KSL cells
Schnackenberg
Tolfenpyrad is used as foliar insecticide for the control of green peach aphids in broccoli
MS645 1378 shows slightly selective over p38βMS645 is a bivalent BET bromodomains (BrD) inhibitor with a Ki of 18. 4 nM for BRD4 BD1 BD2. MS645 spatially constrains bivalent inhibition of BRD4 BrDs resulting in a sustained repression of BRD4 transcriptional activity in solid tumor cells. Product information CAS Number: 2250091 96 2 Molecular Weight: 938. 04 Formula: C48H54Cl2N10O2S2 Chemical Name: 2 [(9S) 7 (4 chlorophenyl) 4,5,13 trimethyl 3 thia 1,8,11,12 tetraazatricyclo[8. 3. 0. 0,]trideca
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