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thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases
InChi: InChI=1S/C24H21FN2O3/c1-15(18-11-12-21(25)20-7-3-2-6-19(18)20)24(30)27-22-13-16(14-26)9-10-17(22)5-4-8-23(28)29/h2-3
GSK1160724) is a potent mAChR antagonist
O=C1NN=C(CC2=CC(=C(F)C=C2)C(=O)N2CC(CNC3CC3)C2)C2=CC=CC=C12
PF-07104091 11388 thus reinforcing selective inhibition ofPF 07104091 is a potent and selective CDK2 cyclin E1 and GSK3 inhibitor, with Kis of 1. 16 and 537. 81 nM, respectively. PF 07104091 has anti tumor activity for cyclin E1 amplified cancers. (patent WO2020157652A2). Product information CAS Number: 2460249 19 6 Molecular Weight: 404. 46 Formula: C19H28N6O4 Chemical Name: (1R,3S) 3 {3 [3 (methoxymethyl) 1 methyl 1H pyrazole 5 amido] 1H pyrazol 5 yl}cyclopentyl N (propan 2 yl)carbamate Smiles:
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