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ALS-008112 enters various types of epithelial cells in the respiratory tract and is subsequently phosphorylated to form an intracellular nucleoside triphosphate with a half-life of approximately 29 hours
Endothelial cells are in fast-growing state (50-60% confluence)
Smiles: CC1N=C(N)SC=1C1=CC=NC(NC2C=CC(=CC=2)N2CCOCC2)=N1
27(3-4):233-42
NAV-2729 19862 ALS-008112 enters various types ofNAV 2729 is a dual Arf1 Arf6 activation inhibitor. Product information CAS Number: 419547 11 8 Molecular Weight: 456. 88 Formula: C25H17ClN4O3 Chemical Name: 2 benzyl 3 (4 chlorophenyl) 5 (4 nitrophenyl) 1H,7H pyrazolo[1,5 a]pyrimidin 7 one Smiles: [O ][N+](=O)C1C=CC(=CC=1)C1=CC(=O)N2NC(CC3C=CC=CC=3)=C(C2=N1)C1C=CC(Cl)=CC=1 InChiKey: WHYGBVWGARJOCS UHFFFAOYSA N InChi: InChI=1S C25H17ClN4O3 c26 19 10 6 18(7 11 19)24 22(14 16 4 2 1 3 5 16)28 29 23(31)15