shows 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases
TPT260 acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~ 5 µM)
an enzyme critical to fatty acid biosynthesis in staphylococci
PubMed Central PMCID: PMC5095872
Ticagrelor-d7 noxynol shows 10- to 100-fold selectivityTicagrelor d7 (AZD6140 d7) is the deuterium labeled Ticagrelor. Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation. Product information CAS Number: 1265911 55 4 Molecular Weight: 529. 61 Formula: C23H28F2N6O4S Chemical Name: (1S,2S,3R,5S) 3 (7 {[(1R,2S) 2 (3,4 difluorophenyl)cyclopropyl]amino} 5 [(1,1,2,2,3,3,3 H)propylsulfanyl] 3H [1,2,3]triazolo[4,5 d]pyrimidin 3 yl) 5 (2