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11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b
Formula: C18H24N9O10P
Formula: C30H32Cl3NO
including the United Kingdom
Taccalonolide A 42112 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[bTaccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri, with cytotoxic and antimalarial activities. Taccalonolide A causes G2 M accumulation, Bcl 2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK OV 3 cells. Product information CAS Number: 108885 68
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