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Smiles: COC1C=C2C(=CC=NC2=CC=1OC)OC1=CC=C(C=C1F)NC(=O)C1=CN(C(C)C)C(=O)N(C2C=CC(F)=CC=2)C1=O
Blood (2-3 mL) and skin (200-300 mg) samples are taken at different time points between 0
Smiles: NC1=N[C@@](C2=CC=CC(F)=C21)(C1C=C(C=CC=1)C1C=NC=NC=1)C1=CC(=NC=C1)C(F)F
No significant mouse body weight loss is observed in Plicamycin-treatment groups
ACT-389949 Size:Contact [email protected] for quotation Smiles: COC1C=C2C(=CC=NC2=CC=1OC)OC1=CC=C(C=C1F)NC(=O)C1=CN(C(C)C)C(=O)N(C2C=CC(F)=CC=2)C1=OACT 389949 is a first in class, potent and selective and agonist of formyl peptide receptor type 2 (FPR2) Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2 ALX internalization into monocytes. ACT 389949 has potential for the treatment of inflammatory disorders. Product information CAS Number: 1258417 54 7 Molecular Weight: 428. 39 Formula: C20H18F2N6O3 Chemical Name: N (2 {[4 (1,1 difluoroethyl) 1,3 oxazol 2 yl]methyl} 2H 1,2,3 triazol 4 yl) 2