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27 uM Target: hLSD1 CBB1007 efficiently can block LSD1-mediated demethylation of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM) with no effect on H3K4Me3 and H3K9Me2
Smiles: FC1C=CC(=CC=1)C1C=C(CN2CCN(CC2)C2=CC=CC3OCCOC=32)C=NC=1
the high-dose astragaloside IV group has a significant increase in the 48-hour survival rate [60% (9/15) vs 13
Chemical Name: 1-(3-chloro-5-{[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1
MO-I-500 ptor Agonist 27 uM Target: hLSD1 CBB1007MO I 500 is the first inhibitor of the RNA demethylase FTO, demonstrating anticonvulsant activity. Product information CAS Number: 1585219 04 0 Molecular Weight: 317. 75 Formula: C12H12ClNO5S Chemical Name: N (3, 4 Dihydroxy 5 (4 chlorophenyl) 2 furanyl)ethanesulfonamide Smiles: CCS(=O)(=O)NC1OC(C2C=CC(Cl)=CC=2)=C(O)C=1O InChiKey: WWHUSZQHRUNRSB UHFFFAOYSA N InChi: InChI=1S C12H12ClNO5S c1 2 20(17,18)14 12 10(16)9(15)11(19 12)7 3 5 8(13)6 4 7 h3 6,14
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