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NGP555 also shows good oral bioavailability and is brain-penetrant with a brain:plasma ratio of ~0
little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM)
inhibits Toll-like receptor 7/9 (TLR7/9) signaling
CAS Number: 112246-15-8
Triglochinic acid opargyl-PEG2-NHS ester NGP555 also shows good oralTriglochinic acid is a monomeric compound isolated from tubers of Pinellia pedatisecta Schott. Product information CAS Number: 31795 12 7 Molecular Weight: 188. 13 Formula: C7H8O6 Chemical Name: (2E) but 2 ene 1,2,4 tricarboxylic acid Smiles: OC(=O)C C=C(\CC(O)=O) C(O)=O InChiKey: PQFOLJLIMNNJQY DAFODLJHSA N InChi: InChI=1S C7H8O6 c8 5(9)2 1 4(7(12)13)3 6(10)11 h1H,2 3H2,(H,8,9)(H,10,11)(H,12,13) b4 1+ Technical Data Appearance: Solid Power Purity:
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