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Tryptamine guanosine carbamate 1788 (2006) Cell

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Description

(2006) Cell

CAS Number: 956906-93-7

XL888 treatment is noted to be proapoptotic in vivo and leads to increased TUNEL staining in M229R xenografts associated with increased expression of BIM and decreased expression of Mcl-1

discussion 21

Tryptamine guanosine carbamate 1788 (2006) CellTryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide binding protein 1) inhibitor (Ki=34 M, Kd=3. 65 M). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance. Product information CAS Number: 1414808 96 0 Molecular Weight: 469. 45 Formula: C21H23N7O6 Chemical Name: [(2R, 3S, 4R, 5R) 5 (2 amino 6 oxo 6, 9 dihydro 3H purin 9 yl) 3, 4 dihydroxyoxolan

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