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m-PEG2-Amine Catalog No.:M14585-10 JH-XI-10-02 induces degradation of CDK8

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Description

JH-XI-10-02 induces degradation of CDK8 at 5 μM in WT Molt4 cells

Dithiothreitol (DTT

The induction of cytotoxicity was associated with inhibition of cell cycle progression and induction of apoptosis in myeloma cell lines and patient-derived plasma cells

very similar to the IC50 values for inhibition of Aβ40 in human embryonic kidney cells overexpressing the Swedish mutation of APP of 0

m-PEG2-Amine Catalog No.:M14585-10 JH-XI-10-02 induces degradation of CDK8m PEG2 Amine is a PEG based PROTAC linker can be used in the synthesis of PROTACs. m PEG2 Amine is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 31576 51 9 Molecular Weight: 119. 16 Formula: C5H13NO2 Chemical Name: 1 (2 aminoethoxy) 2 methoxyethane Smiles: COCCOCCN InChiKey: QWCGXANSAOXRFE UHFFFAOYSA N InChi: InChI=1S C5H13NO2 c1 7 4 5 8 3 2 6 h2 6H2,1H3 Technical Data Appearance:

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