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158(6):1324-34
PF-4708671 specifically inhibits the S6K1 isoform with a Ki of 20 nM and IC50 of 160 nM
reaching a peak after 48 hours of treatment
At the 1 mg/kg dose CC-115 shows significant inhibition at 1 and 3 hours
BAI1 605halidomide-PEG4-COOH 158(6):1324-34BAI1 is a selective and allosteric inhibitor of BAX, an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX dependent cell death. Product information CAS Number: 335165 68 9 Molecular Weight: 467. 20 Formula: C19H21Br2N3O Chemical Name: 1 (3, 6 dibromo 9H carbazol 9 yl) 3 (piperazin 1 yl)propan 2 ol Smiles:
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