Rilmenidine hemifumarate iKan 083 with an IC50 < 100

with an IC50 < 100 nM

TL32711 binds to and inhibits the activity of IAPs

C(CCN1CCN(CCOC(C2C=CC=CC=2)C2C=CC=CC=2)CC1)C1C=CC=CC=1

Formula: C23H24N2O

Rilmenidine hemifumarate iKan 083 with an IC50 < 100Rilmenidine hemifumarate, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine hemifumarate is an alpha 2 adrenoceptor agonist. Rilmenidine hemifumarate induces autophagy. Rilmenidine hemifumarate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na+ H+ antiport. Rilmenidine hemifumarate modulates proliferation and stimulates the proapoptotic