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JTE-607 394Methyl Atorvastatin hemicalcium 19-38)20-39)18-17-33(7)25(29(24)36)9-10-27-32(6)14-13-28(43-23(3)40)31(4

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Description

19-38)20-39)18-17-33(7)25(29(24)36)9-10-27-32(6)14-13-28(43-23(3)40)31(4

a major phytochemical constituent of the essential oil exhibits antibacterial

Acid Yellow 36 changes its color from red at pH 1

5S)-3-{2-[(1R

JTE-607 394Methyl Atorvastatin hemicalcium 19-38)20-39)18-17-33(7)25(29(24)36)9-10-27-32(6)14-13-28(43-23(3)40)31(4JTE 607, a highly selective inflammatory cytokine synthesis inhibitor, protects from endotoxin shock in mice. JTE 607 inhibits inflammatory cytokine production, including TNF , IL 1, IL 6, IL 8 and IL 10, from LPS stimulated human PBMCs, with IC50s of 11, 5. 9, 8. 8, 7. 3 and 9. 1 nM, respectively. Cleavage and Polyadenylation Specificity Factor 3 (CPSF3) is the target of JTE 607. Product information CAS Number: 188791 09 5 Molecular Weight: 597. 36

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